Table 2.
Distribution and population means for betaine (µM) in generally healthy adults.
| Percentile | Normal Healthy Adult Volunteers (n = 501) |
Normal Healthy Adult Volunteers Female (n = 292) |
Normal Healthy Adult Volunteers Male (n = 209) |
PREVEND Study Participants (n = 5621) |
|---|---|---|---|---|
| 0th | <13.2 a | <13.2 a | 24.6 | 13.3 |
| 2.5th | 23.8 | 22.0 | 28.5 | 21.0 |
| 25.0th | 34.1 | 32.4 | 37.3 | 30.8 |
| 50.0th | 41.0 | 39.1 | 44.6 | 36.8 |
| 75.0th | 49.5 | 46.9 | 52.4 | 43.8 |
| 97.5th | 74.7 | 74.4 | 75.3 | 63.0 |
| 100th | 104.1 | 101.6 | 104.1 | 190.7 |
| Mean (SD) | 42.9 (12.6) | 40.7 (12.4) | 46.0 (12.2) | 38.1 (11.2) |
Abbreviations: SD, standard deviation. a Lower bound of the reportable range is limited by the LOQ of this assay.