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. 2019 Nov 18;8(11):1459. doi: 10.3390/cells8111459

Table 2.

Exosomal microRNAs (miRNAs) and their targets that are involved in cancer development.

Cancer miRNAs Target Refs.
Breast cancer miR-10b HOXD10, KLF4 [235]
miR-373 Unknown [230]
miR-200 family members Unknown [236]
miR-1246 Unknown [237]
Esophageal cancer miR-21 PDCD4 [238]
miR-93-5p PTEN [239]
Oral squamous cell carcinoma miR-1246 DENND2D [240]
Glioblastoma miR-301a Unknown [241]
miR-148a CADM1 [242]
Hepatocellular carcinoma miR-665 Unknown [243]
miR-125b Unknown [244]
miR-210 SMAD4, STAT6 [245]
miR-93 TP53INP1,
TIMP2, CDKN1A
[246]
miR-1247-3p B4GALT3 [247]
miR-103 Unknown [248]
Osteosarcoma miR-675 CALN1 [249]
Lung cancer miR-17-3p, miR-21,
miR-106a, miR-146,
miR-155, miR-191,
miR-192, miR-203,
miR-205, miR-210,
miR-212, miR-214
Unknown [228]
miR-21-5p, miR-126-3p,
miR-140-5p
Unknown [250]
miR-193a-3p, miR-210-3p,
miR-5100
Unknown [251]
Ovarian cancer miR-21, miR-141,
miR-200a, miR-200b,
miR-200c, miR-203,
miR-205, miR-214
Unknown [229]
miR-99a-5p Unknown [252]
miR-375, miR-1307 Unknown [253]
Colorectal cancer let-7a, miR-1229,
miR-1246, miR-150,
miR-21, miR-223,
miR-23a
Unknown [231]
miR-6803-5p Unknown [254]
miR-27a, miR-130a Unknown [255]
miR-25-3p KLF2, KLF4 [256]
Prostate cancer miR-200c-3p, miR-21-5p,
let-7a-5p
Unknown [232]
Pancreatic cancer miR-23b-3p Unknown [257]
miR-191, miR-21,
miR-451a
Unknown [258]
Gastric cancer miR-423-5p SUFU [259]
miR-23b Unknown [260]
miR-130a C-MYB [261]
miR-27a Unknown [262]
Acute myeloid leukemia miR-125b Unknown [263]

HOXD10, homeobox D10; KLF4, Krüppel-like factor 4; PDCD4, programmed cell death 4; PTEN, phosphatase and tensin homolog; DENND2D, DENN/MADD domain-containing 2D; CADM1, cell adhesion molecule 1; SMAD4, mothers against decapentaplegic homolog 4; STAT6, signal transducer and activator of transcription 6; TP53INP1, tumor protein p53-inducible nuclear protein 1; TIMP2, TIMP metallopeptidase inhibitor 2; CDKN1A, cyclin-dependent kinase inhibitor 1A; CALN1, calneuron-1; B4GALT3, β-1,4-galactosyltransferase 3; KLF2, Krüppel-like factor 2; SUFU, suppressor of fused homolog; C-MYB, v-myb avian myeloblastosis viral oncogene homolog.