Table 1.
Summary of the effects of FSAP on vascular growth and repair processes.
Habp2-/- Mice: Lack of Endogenous FSAP | Local Application of Exogenous Purified FSAP | |
---|---|---|
Neointima formation in response to intraluminal injury in the femoral artery | Increased [15] | Decreased [18] |
Femoral artery ligation and stimulation of collateral development in the adductor muscle | Increased [16] | Decreased [16] |
Femoral artery ligation and stimulation of angiogenesis in the gastrocnemius muscle | No change [16] | Increased, probably as a consequence of decreased collateral growth [16] |
Matrigel/growth factor model of angiogenesis | No change (this study) | Decreased (this study) |