Table 2.
Baseline and main delivery data in pregnancies from egg donation according to the comorbid conditions considered.
| According to the Main Conditions | p-Value | According to Groups | p-Value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| No Risk | Thyroid | Auto-Immune | Renal | Other | Autoimmune and Thyroid | Renal and Other | |||
| n (%) | 178 (60.1%) | 56 (18.9%) | 19 (6.4%) | 11 (3.7%) | 32 (10.8%) | 75 (25.3%) | 43 (14.5%) | ||
| Age (years), median (min–max) | 44 (31–56) | 43 (33–50) | 44 (34–51) | 43 (34–47) | 45 (33–52) | 0.5956 | 43 (33–51) | 43 (33–52) | 0.7599 |
| Parity, n. first (%) | 151 (84.8%) | 48 (85.7%) | 19 (100%) | 11 (100%) | 30 (93.8%) | 0.1497 | 67 (89.3%) | 41 (95.3%) | 0.2608 |
| BMI (kg·m−2), median (min–max) | 22.7 (16.8–33.7) | 21.5 (17.6–33.3) | 21.8 (19.4–34.4) | 24.6 (18.7–34.0) | 25.2 (15.6–35.5) | 0.2246 | 21.6 (17.6–34.4) | 24.9 (15.6–35.5) | 0.0267 |
| Hypertension during pregnancy, n (%) * | 31 (17.4%) | 18 (32.1%) | 5 (26.3%) | 7 (63.6%) | 13 (40.6%) | 0.0005 | 23 (30.7%) | 20 (40.6%) | 0.0865 |
| Gestational hypertension, n (%) | 31 (17.4%) | 18 (32.1%) | 4 (21.1%) | 5 (45.5%) | 2 (6.2%) | 0.0073 | 22 (29.3%) | 7 (16.3%) | 0.1145 |
| Pre-eclampsia, n (%) | 16 (9.0%) | 6 (10.7%) | 1 (5.3%) | 4 (36.4%) | 6 (18.8%) | 0.0336 | 7 (9.3%) | 10 (23.3%) | 0.0390 |
| Centiles at birth, median (min–max) | 60 (1–100) | 48 (1–99) | 54 (4–100) | 59 (1–95) | 44 (0–90) | 0.0949 | 48 (1–100) | 46 (0–95) | 0.4862 |
| Caesarean section, n (%) | 128 (71.9%) | 39 (69.9%) | 17 (89.5%) | 8 (72.7%) | 18 (56.2%) | 0.0177 | 56 (74.7%) | 26 (60.5%) | 0.0072 |
| Size for GA Small, n (%) Adeq, n (%) Large, n (%) |
12 (6.7%) 138 (77.5%) 28 (15.8%) |
4 (7.1%) 47 (83.9%) 5 (8.9%) |
3 (15.8%) 13 (68.4%) 3 (15.8%) |
3 (27.3%) 7 (63.6%) 1 (9.0%) |
5 (15.6%) 27 (84.4%) 0 (0%) |
0.0595 ** | 7 (9.3%) 60 (80.0%) 8 (10.7%) |
8 (18.6%) 34 (79.1%) 1 (2.3%) |
0.1139 |
| Pre-term <37, n (%) <34, n (%) <32, n (%) |
24 (13.5%) 10 (12.8%) 7 (3.9%) |
9 (16.1%) 3 (5.4%) 2 (3.5%) |
2 (10.5%) 0 0 |
3 (27.3%) 1 (9.0%) 0 |
10 (31.3%) 4 (12.5%) 2 (6.3%) |
0.1014 0.4293 0.7800 |
11 (14.7%) 3 (4.0%) 2 (2.7%) |
13 (30.2%) 5 (11.6%) 2 (4.7%) |
0.0441 0.1142 0.5681 |
eGFR EPI: glomerular filtration rate calculated with the EPI formula; BMI: body mass index; GA: gestational age; PE: preeclampsia; Adeq. Adequate. HT Hypertension * Hypertension in pregnancy: all cases regardless of previous hypertension. Gestational hypertension is hypertension during pregnancy in previously normotensive patients. ** Chi Square test for the difference in the distribution. Significant results in bold.