Table 4.
Comparison of egg donation pregnancies according to serum creatinine and eGFR.
| According to Creatinine (mg/dL) | p-Values | According to eGFR (mL/min) | p-Values | |||
|---|---|---|---|---|---|---|
| sCr ≥ 0.67 | sCr < 0.67 | GFR < 90 | GFR ≥ 90 | |||
| n (%) | 68 (54.8%) | 56 (45.2%) | 38 (30.6%) | 86 (69.4%) | ||
| Age, median (min–max) | 44 (32–55) | 44 (31–56) | 0.8363 | 45 (38–55) | 44 (31–56) | 0.1993 |
| Parity, n. first (%) | 64 (94.1%) | 52 (92.9%) | 0.7770 | 36 (94.7%) | 80 (93.0%) | 0.7214 |
| BMI (kg·m−2), median (min–max) | 22.0 (15.6–35.5) | 22.8 (17.1–34.4) | 0.8889 | 22.3 (15.6–34.0) | 22.8 (17.1–35.5) | 0.8816 |
| No comorbidity, n (%) | 31 (45.6%) | 30 (53.6%) | 0.3781 | 18 (47.4%) | 60 (69.8%) | 0.7878 |
| Centiles at birth, median (min–max) | 54 (0–98) | 55 (1–100) | 0.4483 | 40 (0–98) | 58 (0–100) | 0.1172 |
| Pre-eclampsia, n (%) | 24 (35.3%) | 6 (10.7%) | 0.0015 | 15 (39.5%) | 15 (17.4%) | 0.0085 |
| Hypertension during pregnancy, n (%) * | 43 (63.2%) | 21 (37.5%) | 0.0045 | 29 (76.3%) | 35 (40.7%) | 0.0003 |
| Gestational hypertension, n (%) | 31 (45.6%) | 20 (35.7%) | 0.2681 | 19 (50.0%) | 32 (37.2%) | 0.1838 |
| Creatinine (mg·dL−1), median (min max) | 0.75 (0.67–1.94) | 0.57 (0.26–0.66) | <0.0001 | 0.86 (0.69–1.94) | 0.63 (0.26–0.86) | <0.0001 |
| GFR-EPI (mL·min−1), median (min-max) | 87 (31–114) | 114 (93–151) | <0.0001 | 78 (31–89) | 108 (90–151) | <0.0001 |
| Caesarean section, n (%) | 53 (77.9%) | 45 (80.4%) | 0.7432 | 32 (84.2%) | 66 (76.7%) | 0.3484 |
| Size for GA Small, n (%) Adeq, n (%) Large, n (%) |
9 (13.2%) 55 (80.9%) 4 (5.9%) |
7 (12.5%) 42 (75.0%) 7 (12.5%) |
0.4350 | 6 (15.8%) 29 (76.3%) 3 (7.9%) |
10 (11.6%) 68 (79.1%) 8 (9.3%) |
0.8033 ** |
| Pre-term <37, n (%) <34, n (%) <32, n (%) |
25 (36.8%) 9 (13.2%) 5 (7.4%) |
8 (14.3%) 2 (3.6%) 1 (1.8%) |
0.0050 0.0607 0.1522 |
16 (42.1%) 6 (15.8%) 4 (10.5%) |
17 (19.8%) 5 (5.8%) 2 (2.3%) |
0.0098 0.0728 0.0507 |
eGFR EPI: glomerular filtration rate calculated with the EPI formula; BMI: body mass index; GA: gestational age; PE: preeclampsia; Adeq. Adequate. HT Hypertension. * Hypertension in pregnancy: all cases regardless of previous hypertension. Gestational hypertension is hypertension during pregnancy in previously normotensive patients. ** Chi Square test for the difference in the distribution. Significant results in bold.