Table 1.
Main clinical characteristics of selected CNS tumors with WHO grading [2].
| WHO Grade Type | Tumor Type | Clinical Characteristics | |
|---|---|---|---|
| Low Grade | Grade I | - Ganglioglioma - Gangliocytoma - Craniopharyngioma - Pilocytic astrocytoma - Meningioma - Subependymoma - Choroid plexus papilloma - Pineocytoma |
- Benign - Non-infiltrative - Slow proliferation - Possible curable by surgery - Long-term survival |
| Grade II | - Diffuse Astrocytoma - Pure oligodendroglioma - Pineocytoma - Atypical meningioma |
- Partly infiltrative - Relative slow proliferation - Can recur as higher grade |
|
| High Grade | Grade III | - Anaplastic astrocytoma - Anaplastic oligodendroglioma - Anaplastic ependymoma - Anaplastic meningioma |
- Malignant - Infiltrative - Can recur as high grade |
| Grade IV | - Gliobastoma multiforme (GB) - Ependymoblastoma - Medulloblastoma - Pineoblastoma |
- Most malignant - Highly infiltrative - Rapid proliferation - Aggressive - Quick recurrence - Necrosis |