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. 2019 Nov 18;9(11):985. doi: 10.3390/ani9110985

Table 8.

Effects of probiotics on gene expression levels of claudin-1, occludin and ZO-1 genes in the jejunum barrier function of broilers (day 42) 1.

Items CON CTC PB SEM p-Value
Treatment 2 CON vs. CTC CON vs. PB CTC vs. PB
Claudin-1 1.00 0.93 0.53 0.18 0.18 0.72 0.12 0.14
Occludin 0.99 1.41 0.98 0.31 0.27 0.13 0.87 0.11
ZO-1 1.02 a,b 5.98 a 5.66 a 0.57 <0.01 <0.01 <0.01 0.92

1 CON, control; CTC, chlorotetracycline (75 mg/kg); PB, probiotic (500 mg/kg in phase 1, 300 mg/kg in phase 2); SEM, standard error of the mean. 2 Treatment, the specific p value of the diet effect in the ANOVAs analysis. a,b values in the same row with different letters are significantly different at p < 0.05.