Table 1.
Physiological parameters 10 min before and after ischemic surgery.
| pH | Distal MAP (mmHg) | PaCO2 (mmHg) | PaO2 (mmHg) | Glu (mM) | |
|---|---|---|---|---|---|
| Pre-ischemia | |||||
| Control | 7.38 ± 0.03 | 83.6 ± 8.85 | 37.0 ± 3.92 | 105.2 ± 8.81 | 6.39 ± 1.23 |
| Vehicle | 7.39 ± 0.03 | 83.9 ± 8.53 | 36.7 ± 3.56 | 102.3 ± 8.35 | 6.34 ± 1.09 |
| Control-PEBP1 (10 mg/kg) | 7.43 ± 0.04 | 84.1 ± 9.10 | 37.2 ± 4.09 | 103.1 ± 9.02 | 6.42 ± 0.88 |
| PEP-1-PEBP1 (1 mg/kg) | 7.41 ± 0.04 | 83.4 ± 9.11 | 37.1 ± 4.55 | 104.2 ± 9.44 | 6.37 ± 1.03 |
| PEP-1-PEBP1 (3 mg/kg) | 7.43 ± 0.03 | 83.8 ± 8.95 | 36.8 ± 3.94 | 106.3 ± 9.21 | 6.48 ± 1.31 |
| PEP-1-PEBP1 (10 mg/kg) | 7.42 ± 0.04 | 83.5 ± 8.66 | 37.1 ± 4.45 | 106.9 ± 10.2 | 6.40 ± 1.07 |
| Reperfusion 10 min | |||||
| Control | 7.40 ± 0.04 | 84.8 ± 8.99 | 36.6 ± 3.96 | 107.4 ± 9.81 | 6.46 ± 0.98 |
| Vehicle | 7.37 ± 0.07 | 87.2 ± 10.2 | 39.4 ± 5.18 | 108.1 ± 9.60 | 6.93 ± 1.44 |
| Control-PEBP1 (10 mg/kg) | 7.35 ± 0.09 | 87.5 ± 11.3 | 38.8 ± 4.82 | 110.9 ± 10.8 | 7.05 ± 1.28 |
| PEP-1-PEBP1 (1 mg/kg) | 7.36 ± 0.06 | 88.2 ± 9.58 | 39.6 ± 6.02 | 106.5 ± 10.6 | 7.12 ± 1.36 |
| PEP-1-PEBP1 (3 mg/kg) | 7.37 ± 0.08 | 86.9 ± 9.83 | 38.4 ± 4.88 | 113.1 ± 12.2 | 7.07 ± 1.20 |
| PEP-1-PEBP1 (10 mg/kg) | 7.37 ± 0.10 | 85.2 ± 8.86 | 38.3 ± 5.03 | 109.8 ± 11.2 | 7.19 ± 1.24 |
There are no significant changes in physiological parameters in control, vehicle-treated, control-PEBP1-treated, and PEP-1-PEBP1-treated groups before ischemic surgery and 10 min after reperfusion.