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. 2019 Nov 6;8(11):1889. doi: 10.3390/jcm8111889

Table 6.

Trends in the antibiotic resistance of frequently cultured bacteria over time.

Organism
Antibiotic Resistance
2007–2008
(n = 223 Strains)
n (%)
2012–2013
(n = 211 Strains)
n (%)
2017–2018
(n = 216 Strains)
n (%)
p-Value
Streptococcus species
Amoxicillin/clavulanate 0 (0.0%) 0 (0.0%) 2 (0.9%) 0.082
Macrolide a 8 (3.6%) 10 (4.7%) 13 (6.0%) 0.233
Staphylococcus aureus
Methicillin 2 (0.9%) 1 (0.5%) 2 (0.9%) 0.977
Haemophilus species
Ampicillin 8 (34.8%) 1 (0.5%) 10 (4.6%) 0.532
Klebsiella species
ESBL 1 (0.4%) 1 (0.5%) 16 (7.4%) <0.001
Ciprofloxacin 1 (0.4%) 0 (0.0%) 0 (0.0%) 0.229
Enterobacter species
ESBL 0 (0.0%) 6 (2.8%) 8 (3.7%) 0.007
Ciprofloxacin 0 (0.0%) 0 (0.0%) 0 (0.0%) N/A
Pseudomonas aeruginosa
ESBL 0 (0.0%) 0 (0.0%) 0 (0.0%) N/A
Ciprofloxacin 0 (0.0%) 0 (0.0%) 2 (0.9%) 0.082

N/A, not available; ESBL, extended-spectrum beta-lactamase; a Macrolide includes azithromycin, erythromycin, and clarithromycin.