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. 2019 Nov 14;8(11):552. doi: 10.3390/antiox8110552

Figure 6.

Figure 6

Effects of AgNPs exposure on the mitochondrial respiration. (a) Oxygen consumption rate (OCR) measured by Seahorse MitoStress assay. a: addition of 10 μg/mL AgNPs for 1 h exposure or vehicle media for the untreated controls and samples pre-treated with 10 μg/mL AgNP for 23 h, b: oligomycin, c: FCCP, d: Antimycin A/Rotenone. (b) Comparison of spare respiratory capacity in different cell lines. (c) Comparison of coupling efficiency in different cell lines. (d) Quantification of key parameters of mitochondrial function. Data are presented as mean value, the error bars represent the standard error of the mean. Statistical values were calculated using Students’ t-test.