Table 5.
Statistical analysis with the classification of thyroid lesions into appropriate EU-TIRADS categories and in relation to their size and malignancy risk. Not applicable (NA) is presented to avoid dividing by zero.
| EU- TIRADS Score | Diameter (mm) | Benign | Malignant | Accuracy (%) (95% CI) | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | PPV (%) (95% CI) | NPV (%) (95% CI) | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
| 3 | ≤20 | 53 | 2 | 58.1 (47.4–68.2) | 33.3 (0.8–90.6) | 58.9 (48–69.2) | 2.6 (0.1–13.8) | 96.4 (87.5–99.6) | 0.72 (0.06–8.19) |
| >20 | 37 | 1 | |||||||
| ≤15 | 38 | 2 | 41.9 (31.8–52.6) | 33.3 (0.8–90.6) | 42.2 (31.9–53.1) | 1.9 (0–10.1) | 95.0 (83.1–99.4) | 0.37 (0.03–4.18) | |
| >15 | 52 | 1 | |||||||
| ≤10 | 17 | 1 | 20.4 (12.8–30.1) | 66.7 (9.4–99.2) | 18.9 (11.4–28.5) | 2.7 (0.3–9.3) | 94.4 (72.7–99.9) | 0.47 (0.04–5.44) | |
| >10 | 73 | 2 | |||||||
| ≤5 | 0 | 0 | 3.2 (0.67–9.14) | 100 (29.24–100.0) | 0 (0.0–4.02) | 3.2 (0.67–9.14) | NA | NA | |
| >5 | 90 | 3 | |||||||
| 4 | ≤15 | 46 | 7 | 49.5 (39.5–59.5) | 41.7 (15.2–72.3) | 50.5 (39.9–61.2) | 10.0 (3.3–21.8) | 86.8 (74.7–94.5) | 0.73 (0.22–2.47) |
| >15 | 45 | 5 | |||||||
| ≤10 | 19 | 5 | 25.2 (17.2–34.8) | 58.3 (27.7–84.8) | 20.9 (13.1–30.7) | 8.9 (3.6–17.4) | 79.2 (57.8–92.9) | 0.37 (0.11–1.29) | |
| >10 | 72 | 7 | |||||||
| ≤5 | 0 | 1 | 10.7 (5.5–18.3) | 91.7 (61.5–99.8) | 0.0 (0.0–4.0) | 10.8 (5.5–18.5) | 0.0 (0.0–97.5) | NA | |
| >5 | 91 | 11 | |||||||
| 5 | ≤10 | 82 | 72 | 45.5 (41.1–50.0) | 66.4 (59.6–72.7) | 29.5 (24.2–35.2) | 42.0 (36.7–47.5) | 53.2 (45–61.3) | 0.83 (0.56–1.21) |
| >10 | 196 | 142 | |||||||
| ≤5 | 8 | 6 | 43.9 (39.5–48.4) | 97.2 (94.0–99.0) | 2.9 (1.3–5.6) | 43.5 (39.0–48.1) | 57.1 (28.9–82.3) | 1.03 (0.35–3.01) | |
| >5 | 270 | 208 |
PPV—positive predictive value, NPV—negative predictive value, OR—odds ratio.