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Adipose interferon regulatory factor-5 (IRF5) gene expression correlates with the circulatory C-reactive protein (CRP) and adiponectin levels. Plasma levels of CRP and adiponectin were measured in 35 individuals including lean, overweight, and obese by ELISA as described in Materials and Methods. The data (mean ± SEM) show that (A) adipose expression of IRF5 correlated positively with CRP levels (r = 0.37, P = 0.03) and (B) negatively with adiponectin levels (r = −0.43, P = 0.009).
