Table 4.
Arm A | Arm B | Arm C | |
---|---|---|---|
NEONAX | Neoadjuvant nab-P+gem + surgery + adjuvant nab-P + Gem | Surgery + adjuvant nab-P + Gem | |
NEOPAC | Neoadjuvant gem + surgery+ adjuvant gem | Neoadjuvant Oxaliplatin + surgery + adjuvant gem | Surgery + adjuvant gem |
NEPAFOX | Neoadjuvant mFOLFIRINOX | Adjuvant mFOLFIRINOX | Adjuvant gem |
NorPACT-1 | Neoadjuvant mFOLFIRINOX + surgery + adjuvant gem plus cape | Surgery + adjuvant gemcitabine plus capecitabine | |
PANACHE01-PRODIGE48 | Neoadjuvant mFOLFIRINOX + surgery + adjuvant therapy | Neoadjuvant FOLOX + surgery + adjuvant therapy | |
PREOPANC-2 | Neoadjuvant mFOLFIRINOX | Neoadjuvant gem-based chemoradiotherapy | |
ESPAC-5 | Neoadjuvant mFOLFIRINOX or Gem plus cape | Neoadjuvant chemoradiotherapy | Up front surgery |
Gem = gemcitabine; nab-P = nab-paclitaxel; mFOLFIRINOX = combination chemotherapy with fluorouracil, leucovorin, irinotecan, and oxaliplatin; FOLFOX = combination chemotherapy with fluorouracil, leucovorin and oxaliplatin.