Table 1.
Key demographics of subjects enrolled in the DOVE study in the different geographic regions.
| Parameter Assessed | Geographic Regions a | Total (N = 341) | p-Value | |||
|---|---|---|---|---|---|---|
| SSA (N = 148) | Americas (N = 57) | North Africa/Middle East (N = 110) | Europe (N = 26) | |||
| Mean Age in Years (SD) | 9.7 (3.9) | 11.1 (4.2) | 12.0 (4.6) | 8.7 (4.3) | 10.6 (4.3) | 0.020 |
| Age Group (n (%)) | <0.001 | |||||
| 2 to <6 years | 32 (21.6) | 9 (15.8) | 17 (15.5) | 9 (34.6) | 67 (19.6) | |
| 6 to <12 years | 72 (48.6) | 22 (38.6) | 29 (26.4) | 9 (34.6) | 132 (38.7) | |
| 12 to <18 years | 44 (29.7) | 26 (45.6) | 64 (58.2) | 8 (30.8) | 142 (41.6) | |
| Gender (n (%)) | 0.733 | |||||
| Female | 75 (50.7) | 32 (56.1) | 52 (47.3) | 14 (53.8) | 173 (50.7) | |
| Race (n (%)) b | <0.001 | |||||
| White | 0 (0.0) | 1 (1.8) | 110 (100.0) | 5 (19.2) | 116 (34.1) | |
| Black or African American | 148 (100.0) | 54 (96.4) | 0 (0.0) | 20 (76.9) | 222 (65.3) | |
| Multiple | 0 (0.0) | 1 (1.8) | 0 (0.0) | 1 (3.8) | 2 (0.6) | |
Abbreviations: N = number of subjects in the specified category; N = number of randomized subjects; SD = standard deviation; SSA = Sub-Saharan Africa. (a) The SSA subgroup includes Ghana and Kenya; the Americas subgroup includes Brazil, the United States, and Canada; the North Africa/Middle East subgroup includes Saudi Arabia, Oman, Egypt, Lebanon, and Turkey; the Europe subgroup includes Belgium, Italy, and the United Kingdom (Heeney et al.) [9]. (b) Refers to self-reported race.