AASP |
Aging-associated secretory phenotype |
ALS |
Amyotrophic lateral sclerosis |
CCL-2 |
C-C motif chemokine ligand 2 |
Cdk/CdkI |
Cyclin-dependent kinase/Cyclin-dependent kinase inhibitor |
cGAS |
Cyclic guanosine monophosphate – adenosine monophosphate synthase |
CSF |
Colony-stimulating factor |
CXCL |
Chemokine C-X-C motif ligand |
DDR |
DNA damage response |
DNA-SCARS |
DNA segments with chromatin alterations reinforcing senescence |
DPP4 |
Dipeptidyl peptidase-4 |
FoxO |
Forkhead box protein O |
GH |
Growth hormone |
HLA |
Human leukocyte antigen |
HR |
Homologous recombination |
IGF-1 |
Insulin-like growth factor-1 |
iPSCs |
Inducible pluripotent stem cells |
LINE-1 |
Long interspersed nuclear element-1 |
LTR |
Long terminal repeats |
MAPK |
Mitogen-activated protein kinase |
MMP |
Matrix-metalloprotease |
mTOR |
Mechanistic target of rapamycin |
NF-κB |
Nuclear factor κB |
NK cell |
Natural killer cell |
OIS |
Oncogene-induced senescence |
PI3K |
Phosphoinositid-3-kinase |
PML |
Promyelocytic leukemia protein |
ROS |
Reactive oxygen species |
RS |
Replicative senescence |
SA-β-Gal |
Senescence-associated-β-galactosidase |
SAHF |
Senescence-associated heterochromatic foci |
SASP |
Senescence associated secretory phenotype |
SIPS |
Stress-induced premature senescence |
STH |
Somatotropin |
STING |
Stimulator of interferon genes |
TC-NER |
Transcription-coupled nucleotide excision repair |