Figure 1.

miR-29b regresses in-vivo prostate tumor growth. PC3 cells were injected subcutaneously into the flank of nude mice. When tumor volume reached ~70 mm³, mice were divided into two groups and 10 µg of miR-29b mimic or control oligoes were injected intratumorally at an interval of 4 days. (A) Representative tumors from control and experimental mice are presented. (B) Tumor volume was monitored twice weekly and presented as a mean. Small bar indicates standard error (*, p < 0.05, ** p < 0.01). Up arrows indicate treatment time points. (C) Relative expression of miR-29b in control and experimental tumors analyzed by qRT-PCR. U6 gene was used as internal control. Small bar indicates standard error (*, p < 0.05).