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. 2019 Nov 12;10(12):1592–1602. doi: 10.1021/acsmedchemlett.9b00425

Table 1. Representative Assays and Techniques for Assessment LDD in Cells.

assay cell lysates live cells target engagement ternary complex formation ubiquitination proteosome trafficking degradation
Western blot          
enzyme-linked immunosorbent assay (ELISA)          
multiplexed immunoassays          
proteomics        
enzyme fragment complementation        
protein fusion tags        
bioluminescence