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. 2019 Dec 16;19:324. doi: 10.1186/s12883-019-1534-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Monthly patient counts and female ratio (a) and average age of MS patients (b) by calendar year and month in the MDV database. The number of MS patients has increased in recent years and the female ratio was constant (65–67%) after August 2008 (a). The average age of patients was stabilized (48–52 years) after April 2010 (b)