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. 2019 Dec 16;17:420. doi: 10.1186/s12967-019-02176-z

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© The Author(s) 2019

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Serum levels of polymorphonuclear (PMN) elastase in patients with myositis. PMN elastase levels are elevated in patients with idiopathic inflammatory myopathies (IIMs) and dermatomyositis (DM), but not in those with polymyositis (PM) when compared with healthy controls (HCs) (a). Area under receiver operating characteristic (ROC) curve analysis was used to assess the ability of PMN elastase to distinguish among IIMs, DM, and HCs (b). The reference curve is also shown. PMN elastase levels were significantly higher in patients with IIMs, DM, and PM with active disease [A] than those in remission [R] (c)