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. 2019 Dec 16;19:293. doi: 10.1186/s12872-019-01284-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The Chinese pedigree with CHD. a Vision-impaired individuals are indicated by blackened symbols. b Identification of the 15910C > T mutation in the tRNA gene. Partial sequences chromatograms of tRNA gene from the proband and one Chinese control. c The location of the 15910C > T mutation in the mitochondrial tRNA^Thr. An arrow indicates the location of the base changes at position 15,910