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. 2019 Nov 21;8(23):e013572. doi: 10.1161/JAHA.119.013572

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© 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Plasma S100ß (A), matrix metalloproteinase‐9 (MMP‐9, B), and neuron‐specific enolase (NSE, C) on days 1 and 4 by treatment group. S100ß levels increase by day 4 in the sham group from 34.5 pg/mL (SD 37.8) to 145.6 pg/mL (309.1), mean difference 111 pg/mL (95% CI, 5.6–216; P=0.041*). There were no significant between‐group differences at day 4. Analysis by repeated measures ANCOVA, Sidak correction for multiple comparisons, and adjusted for baseline stroke severity. RIC indicates remote ischemic conditioning.