Table 3.
Functional Outcome by Group at Day 4 and Day 90
| Functional Measure | RIC | Sham | P Value |
|---|---|---|---|
| Day 4a | n=30 | n=24 | |
| NIHSS | 6.4 (9.4) | 9.5 (12.8) | 0.30 |
| Change NIHSS | −3.0 (3.8) | −1.4 (6.3) | 0.35 |
| Day 90 | n=31 | n=29 | |
| mRS (/6) | |||
| Median | 2 [1–4] | 2 [1–3] | 0.85 |
| mRS 3 to 6 | 12 (40) | 14 (46.6) | 0.46 |
| Barthel Index (/100) | 100 [65–100] | 100 [57.5–100] | 0.89 |
| Zung depression scoreb | 46.25 [33.75–53.75] | 42.5 [37.5–52.5] | 0.94 |
| EuroQoL HUIb | 0.514 (0.377) | 0.482 (0.393) | 0.77 |
| EuroQoL VASb | 70.8 (23.0) | 69.8 (19.2) | 0.87 |
| TICS‐Mb | 23 [20–25] | 23.5 [21–27] | 0.89 |
Data are expressed as mean (SD), median [interquartile range], or number (percentage). Imputed value for death: Barthel index −5; National Institutes of Health Stroke Scale (NIHSS) 42. mRS indicates modified Rankin Scale.
Day 4 NIHSS—sham n=24, remote ischemic conditioning (RIC) n=30 (data missing attributable to early discharge or refused). Analyzed by independent t test, Mann–Whitney U test, or chi‐square test as appropriate.
Number for EuroQoL Health Utilities Index (HUI): 24 (sham)/28 (RIC), EuroQoL visual analogue scale (VAS) 22/24, Zung 17/16, and Modified Telephone Interview for Cognitive Status (TICS‐M) 14/14. Number reduced by: (1) carers answering on behalf of participants who could not respond (n=17), (2) refused to answer questions on mood and cognition, and (3) death (n=6).