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. 2019 Dec 9;10:1468. doi: 10.3389/fphar.2019.01468

Table 2.

Characteristics of eye involvement distinguished by different biosimilars employed at the time of the switch.

Biosimilars employed Non-Anterior Uveitis, n (%) Patients with BD, n (%) Patients with idiopathic uveitis, n (%) BCVA, mean ± SD CMT,
mean ± SD
UME, n (%) Retinal vasculitis, n (%) Eyes with uveitic complications, n (%) cDMARDs coadministered, n (%) Eyes with flares during the 12 months before, n (%)
Flixabi® (n = 16) 12 (75) 13 (81.3) 3 (18.8) 7.23 ± 2.4 288.6 ± 35.6 5 (31.3) 6 (37.5) 4 (25) 5 (31.3) 3 (18.8)
Inflectra® (n = 9) 9 (100) 9 (100) 0 (0) 6.9 ± 4.2 295 ± 30.3 2 (22.2) 0 (0) 3 (33.3) 2 (22.2) 1 (11.1)
Imraldi® (n = 33) 22 (66.7) 22 (66.7) 4 (12.1) 9.3 ± 1.9 275.9 ± 43.1 2 (6.1) 0 (0) 5 (15.2) 7 (21.2) 7 (21.2)
Benepali® (n = 4) 1 (25) 0 (0) 0 (0) 6.5 ± 2.1 287.5 ± 24.7 0 (0) 0 (0) 0 (0) 2 (50) 0 (0)

BCVA, best corrected visual acuity; BD, Behçet’s disease; cDMARDs, conventional disease modifying anti-rheumatic drugs; CMT, central macular thickness; n, number of eyes; UME, uveitic macular edema.