FIG. 3.

HIV-specific IFN-γ ELISpot responses. IFN-γ ELISpot responses in vaccinees after stimulation with Gag DNA, Gag CMDR, Env CMDR, and Pol CMDR peptide pools (A) 2 weeks after the third HIV-DNA immunization, (B) 2 weeks after the first HIV-MVA vaccination, and (C) 2 weeks after the second HIV-MVA vaccination. The number of responders per number of evaluable vaccinees is given in brackets. The bars show median values. ELISpot responses were considered positive if the number of SFCs was >55 spots/million PBMCs and four times the background value. The dashed line is at 55 SFCs/million PBMCs. Responders are shown by filled symbols and nonresponders are shown by open symbols.