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. Author manuscript; available in PMC: 2019 Dec 16.
Published in final edited form as: Clin Gastroenterol Hepatol. 2017 Sep 28;16(6):800–808.e7. doi: 10.1016/j.cgh.2017.09.033

Table 2.

Studies That Reported pH Time > 4

Studies Study arms, na

Randomized study arms 146
Patient population
 Healthy   94
 Heartburn/GERD/esophagitis   38
 Duodenal ulcer     7
 Barrett’s esophagus     7
Dosing
 Daily 116
 Twice daily   25
 Three times daily     5
Days of therapy before testing
 5–6 100
 7–9   32
 ≥10   14

GERD, gastroesophageal reflux disease.

a

For ease of interpretation, the table shows study arms. Some studies have multiple study arms included. A total of 56 studies, comprising 148 studies, were included.