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. Author manuscript; available in PMC: 2019 Dec 16.
Published in final edited form as: Clin Gastroenterol Hepatol. 2017 Sep 28;16(6):800–808.e7. doi: 10.1016/j.cgh.2017.09.033

Table 3.

PPI Cost: Brand vs Generic PPIs

Drug OE Cost Cost per OE


Brand price Generic median price
(minimum-maximum price)
Brand Generic (based on
median price)

Pantoprazole
 20 mg   4.5 $14.38 $4.09 ($0.13-$10.79) $3.19 $0.91
 40 mg   9 $14.37 $0.33 ($0.13-$10.79) $1.60 $0.04
Omeprazole
 10 mg 10 - $3.77 ($0.22-$3.99) - $0.38
 20 mg 20 - $0.64 ($0.07-$8.79) - $0.03
 40 mg 40 - $7.40 ($0.15-$7.40) - $0.18
Lansoprazole
 15 mg 13.5 $16.60 $0.60 ($0.16-$6.01) $1.23 $0.04
 30 mg 27 $16.60 $4.25 ($2.05-$13.24) $0.61 $0.16
Esomeprazole
 20 mg 32 $10.04 $8.52 ($0.65-$9.02) $0.31 $0.27
 22.3 mg 35.7 $0.70 ($0.65-$0.77) - $0.02
 40 mg 64 $10.04 $8.64 ($4.50-$9.02) $0.16 $0.13
Rabeprazole
20 mg 36 $20.79 $2.75 ($1.20-$11.46) $0.58 $0.08
Dexlansoprazole
 30 mg N/A   $9.76 N/A - -
 60 mg N/A   $9.76 N/A - -

NOTE. Drugs are presented in order of increasing potency and only forsolid dosage formulations (ie, excluded sprinkle and liquid formulations). Drugs are ordered in terms of potency based on OEs.

OE, omeprazole equivalent; PPIs, proton pump inhibitors.