Table 2. Different clinical presentations of pyoderma gangrenosum and their associated systemic diseases 3, 4, 22, 23.
Variant of pyoderma
gangrenosum |
Common location | Presentation | Associated disease |
---|---|---|---|
Ulcerative (classic) | Lower extremities | Rapid progression
Violaceous undermined border Very painful |
Inflammatory bowel disease (IBD)
Arthritis Myeloproliferative disease |
Bullous | Face | Superficial bulla
Blue-gray border |
Myeloproliferative disease (that is, acute
myeloid leukemia) |
Pustular | Legs
Upper trunk |
Painful pustules
Red halo |
IBD |
Vegetative | Trunk | Superficial ulcer
No violaceous border |
None |
Peristomal | Near stoma site | Painful ulcer
Violaceous undermined border |
IBD
Enteric malignancies |
Post-surgical (procedural)
(after nipple piercing) |
Surgery site (breast,
abdomen most common) |
Rapid progression
Active and undermined border Pain out of proportion to lesion |
Fewer cases of underlying systemic disease
(compared with classic form) 23 |
Pyostomatitis vegetans | Buccal gingiva, labial and
buccal mucosa |
Multiple small white or yellow pustules
Erythema Edema |
IBD |