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. 2019 Nov 27;19(1):619–629. doi: 10.3892/etm.2019.8250

Table I.

Amplitude and latency of flash-visual evoked potential.

A, Latency of N1-P1 waves, µV (n=10)

Timepoint Sham ONC NC-shRNA Lingo-shRNA P-value
Pre ONC 43.97±6.93 45.37±4.35 47.33±2.99 0.662
2 weeks 45.23±4.07 65.86±6.37 55.98±5.04 0.002
4 weeks 49.23±3.69 59.03±3.94 50.88±6.45 0.0004

B, Amplitude of N1 waves, ms (n=10)

Timepoint Sham ONC NC-shRNA Lingo-shRNA P-value
Pre ONC 32.7±2.14 32.37±2.53 33.43±2.99 0.554
2 weeks 33.03±4.73 5.65±0.68 14.35±3.29 0.011
4 weeks 36.27±7.81 5.27±3.56 17.06±2.89 0.002

Data are presented as the mean ± standard error. Lingo-1, leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; ONC, optic nerve crush; NC-shRNA, negative control shRNA; shRNA, short hairpin RNA.