Table 2.
The Genotype Distribution of CXCL14 Polymorphisms and Its Association with Chronic HBV Progression
| Genotype | Group 1 | Group 2 | Group 3 | P value | OR (95% CI)a |
|---|---|---|---|---|---|
| rs2237061 | |||||
| CC | 110 (72.8) | 43 (70.5) | 132 (73.3) | 0.129a | 1.00 (Ref) |
| CT | 33 (21.9) | 10 (16.4) | 39 (21.7) | 0.991b | 0.78 (0.35–1.71) |
| TT | 8 (5.3) | 8 (13.1) | 9 (5.0) | 0.081c | 2.56 (0.90–7.25) |
| C | 253 (83.8) | 96 (78.7) | 303 (84.2) | 0.214 a | 1.00 (Ref) |
| T | 49 (16.2) | 26 (21.3) | 57 (15.8) | 0.891 b | 1.40 (0.82–2.38) |
| 0.166 c | |||||
| rs2237062 | |||||
| GG | 76 (50.3) | 25 (41.0) | 97 (53.9) | 0.006a* | 1.00 (Ref) |
| GC | 64 (42.4) | 22 (36.1) | 79 (43.9) | 0.087b | 1.05 (0.54–2.03) |
| CC | 11 (7.3) | 14 (23.0) | 4 (2.2) | <0.001c* | 3.87 (1.56–9.61)* |
| G | 216 (71.5) | 72 (59.0) | 273 (75.8) | 0.012 a | 1.00 (Ref) |
| C | 86 (28.5) | 50 (41.0) | 87 (24.2) | 0.209 b | 1.74 (1.13–2.71) |
| <0.001 c | |||||
| rs2547 | |||||
| GG | 124 (82.1) | 46 (75.4) | 153 (85.0) | 0.004a* | 1.00 (Ref) |
| GA | 26 (17.2) | 9 (14.8) | 26 (14.4) | 0.773b | 0.93 (0.41–2.14) |
| AA | 1 (0.7) | 6 (9.8) | 1 (0.56) | 0.001c* | 16.17 (1.90–138.00)* |
| G | 274 (90.7) | 101 (82.8) | 332 (92.2) | 0.021 a | 1.00 (Ref) |
| A | 28 (9.3) | 21 (17.2) | 28 (7.8) | 0.492b | 2.04 (1.11–3.75) |
| 0.003c |
Notes: aGroup 1 vs Group 2. bGroup 1 vs Group 3. cGroup 2 vs Group 3. *P<0.05