Table 3.
Comparison on Liver Function Parameters Among Patients with Chronic HBV Infection by CXCL14 Polymorphisms
| Liver Function Parameters | rs2237062 GG Genotype | GC+CC Genotype | P value | rs2547 GG Genotype | GA+AA Genotype | P value |
|---|---|---|---|---|---|---|
| TBIL (umol/L) | 18.14±6.18 | 29.79±4.06 | 0.003* | 24.61±7.02 | 25.33±4.84 | 0.901 |
| DBIL (umol/L) | 4.13±3.96 | 9.92±4.91 | 0.013* | 7.42±8.68 | 7.38±5.26 | 0.991 |
| IBIL (umol/L) | 15.72±10.19 | 19.92±17.23 | 0.028* | 18.13±14.85 | 17.95±14.27 | 0.947 |
| AST (U/L) | 277.57±74.91 | 304.66±56.24 | 0.530 | 251.27±52.12 | 489.78±57.56 | 0.004* |
| ALT (U/L) | 146.78±32.42 | 174.93±26.82 | 0.274 | 127.53±30.20 | 329.16±20.75 | 0.001* |
| TP (g/L) | 73.37±8.28 | 74.37±4.55 | 0.265 | 74.28±4.50 | 72.30±11.91 | 0.089 |
| GLOB (g/L) | 41.34±5.33 | 42.48±3.48 | 0.077 | 42.18±3.54 | 41.03±7.22 | 0.147 |
| ALB (g/L) | 32.43±4.44 | 31.89±3.84 | 0.351 | 32.10±4.01 | 32.24±4.64 | 0.852 |
| TF (g/L) | 226.42±31.25 | 231.77±32.92 | 0.230 | 228.07±32.10 | 235.95±32.57 | 0.178 |
| CP (g/L) | 24.77±3.64 | 23.94±4.43 | 0.138 | 24.07±3.84 | 25.36±5.15 | 0.086 |
| HA (ug/L) | 98.03±8.07 | 117.34±9.78 | 0.124 | 98.64±7.50 | 157.78±7.87 | 0.023* |
Note: * P<0.05.
Abbreviations: TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin; ALT, alanine aminotransferase; AST, aspartate transaminase; TP, total protein; GLOB, globulin; ALB, albumin; TF, transferrin; CP, ceruloplasmin; HA, Hyaluronan.