Table 1.
Variables | Epileptic patients (N = 100) | Patient group (N = 50) | Control group (N = 50) | ||||
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n | % | n | % | n | % | ||
Sex ratio | Male | 56 | 56 | 28 | 56 | 28 | 56 |
Female | 44 | 44 | 22 | 44 | 22 | 44 | |
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Age (years) | 6.710 ± 4.358 | 6.220 ± 4.432 | 7.200 ± 4.271 | ||||
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Age at seizure onset (years) | 3.820 ± 3.362 | 2.680 ± 2.470 | 4.960 ± 3.752 | ||||
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Type of seizure | Generalized | 75 | 75 | 42 | 84 | 33 | 66 |
Focal | 20 | 20 | 3 | 6 | 17 | 34 | |
Focal to bilateral tonic-clonic | 5 | 5 | 5 | 10 | 0 | 0 | |
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Epileptic syndrome | Yes | 26 | 26 | 19a | 38 | 7b | 14 |
No | 74 | 74 | 31 | 62 | 43 | 86 | |
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Etiology of epilepsy | Autoimmune | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic | 31 | 31 | 24 | 48 | 7 | 14 | |
Infectious | 1 | 1 | 0 | 0 | 1 | 2 | |
Metabolic | 1 | 1 | 0 | 0 | 1 | 2 | |
Structural | 10 | 10 | 0 | 0 | 10 | 20 | |
Unknown | 57 | 57 | 26 | 52 | 31 | 62 | |
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Medical history | Yes | 16 | 16 | 8c | 16 | 8d | 16 |
No | 84 | 84 | 42 | 84 | 42 | 84 | |
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Antiepileptic treatment | Monotherapy | 34 | 34 | 0 | 0 | 34e | 68 |
Bitherapy | 24 | 24 | 8f | 16 | 16g | 32 | |
Polytherapy | 42 | 42 | 42h | 84 | 0 | 0 |
Values (n and %). aAbsences, Angelman, continuous spikes and waves during sleep (CSWS), Dalla Benardina, Doose, Dravet, Ohtahara, early myoclonic encephalopathy (EME), generalized epilepsy with febrile seizures plus (GEFS+), juvenile myoclonic epilepsy (JME), Lennox-Gastaut, WEST. bAbsences, benign epilepsy with centro-temporal spikes (BECTS), early myoclonic encephalopathy (EME), idiopathic generalized epilepsies (IGE), tuberous sclerosis of Bourneville (STB). cAppendectomy, bronchopneumopathy, dehydration and gastroenteritis, febrile seizures, mental retardation with behavioral disorder, neonatal cyanosis, recurrent bilateral otitis media, recurrent urinary tract infections, varicella dAppendectomy, bilateral hernia, bilateral testicular ectopia, enuresis, febrile seizures, gastroesophageal reflux, trauma, maternal-feotal infection, mumps, neonatal hypoglycemia, strabismus, stunting delay. eControls were prescribed single AED (carbamazepine or valproic acid). fPatients were prescribed a combination of 2 AEDs (carbamazepine, clonazepam, lamotrigine, phenobarbital, valproic acid, vigabatrin). gControls were prescribed a combination of 2 AEDs (carbamazepine, clonazepam, phenobarbital, valproic acid). hPatients were prescribed a combination of diverse AEDs (carbamazepine, clobazam, clonazepam, diazepam, ethosuximide, lamotrigine, levetiracetam, phenobarbital, phenytoin, topiramate, valproic acid, vigabatrin).