Table 4.

Distribution of ABCB1 genotypes frequencies in drug-responsive and drug-resistant patients.

SNP	ABCB1 genotype	Drug-resistant patients (N = 50)		Drug-responsive patients (N = 50)		ORs	95% CI	p value	X 2
		n	%	n	%
ABCB1 C1236T	CC vs. CT+TT	6	12	17	34	0.265	0.094-0.745	0 .012	6.830
	CT vs. CC+TT	18	56	27	54	0.479	0.215-1.068	0.072	3.270
	TT vs. CC+CT	26	52	6	12	7.944	2.872-21.978	≤0.001	18.380
	TT vs. CC	26	52	6	12	12.278	3.393-44.433	≤0.001	16.740
	CT vs. CC	18	56	27	54	1.889	0.625-5.705	0.260	2.890
	TT vs. CT	26	52	6	12	6.500	2.231-18.940	≤0.001	12.990
ABCB1 G2677T	GG vs. GT+TT	10	20	3	6	3.917	1.008-15.220	0.049	4.330
	GT vs. GG+TT	13	26	41	82	0.077	0.030-0.201	≤0.001	31.560
	TT vs. GG+GT	27	54	6	12	8.609	3.110-23.832	≤0.001	19.950
	TT vs. GG	27	54	6	12	1.350	0.282-6.453	0.707	0.140
	GT vs. GG	13	26	41	82	0.095	0.023-0.399	0.001	12.980
	TT vs. GT	27	54	6	12	14.192	4.808-41.895	0.001	27.500
ABCB1 C3435T	CC vs. CT+TT	11	22	24	48	0.306	0.128-0.729	0.008	7.430
	CT vs. CC+TT	9	18	20	40	0.329	0.132-0.824	0.018	5.880
	TT vs. CC+CT	30	60	6	12	11	3.952-30.614	≤0.001	25
	TT vs. CC	30	60	6	12	10.909	3.523-33.782	≤0.001	19.590
	CT vs. CC	9	18	20	40	0.982	0.339-2.840	0.973	0
	TT vs. CT	30	60	6	12	11.111	3.422-36.081	≤0.001	18.300

Values (n and %). ORs: odds ratio; 95% CI: confidence interval; significant p value ≤ 0.05; X²: chi-square.