Table 5.
SNP | ABCB1 allele | Drug-resistant patients (N = 50) (%) | Drug-responsive patients (N = 50) (%) | ORs | 95% CI | p value | X 2 |
---|---|---|---|---|---|---|---|
ABCB1 C1236T | C | 30 | 61 | 0.274 | 0.152-0.493 | ≤0.001 | 19.380 |
T | 70 | 39 | 3.650 | 2.029-6.563 | ≤0.001 | ||
| |||||||
ABCB1 G2677T | G | 33 | 47 | 0.555 | 0.313-0.985 | 0.044 | 4.080 |
T | 67 | 53 | 1.801 | 1.016-3.192 | 0.044 | ||
| |||||||
ABCB1 C3435T | C | 31 | 68 | 0.211 | 0.116-0.384 | ≤0.001 | 27.380 |
T | 69 | 32 | 4.730 | 2.604-8.591 | ≤0.001 |
Values (n and %). ORs: odds ratio; 95% CI: confidence interval; significant p value ≤ 0.05; X2: chi-square.