Table 6.
Haplotype frequencies of the ABCB1 C1236T and G2677T polymorphisms in drug-responsive and drug-resistant patients.
| ABCB1 C1236T-G2677T haplotype | Drug-resistant patients (N = 50) | Drug-responsive patients (N = 50) | ORs | 95% CI | p value | X 2 | ||
|---|---|---|---|---|---|---|---|---|
| n | % | n | % | |||||
| CG | 10 | 20 | 39 | 78 | 0.071 | 0.027-0.185 | ≤0.001 | 33.650 |
| CT | 14 | 28 | 5 | 10 | 3.500 | 1.152-10.633 | 0.027 | 5.260 |
| TG | 12 | 24 | 5 | 10 | 2.842 | 0.919-8.791 | 0.070 | 3.470 |
| TT | 14 | 28 | 1 | 2 | 19.056 | 2.395-151.604 | 0.005 | 10.700 |
Values (n and %). ORs: odds ratio; 95% CI: confidence interval; significant p value ≤ 0.05; X2: chi-square.