Table 8.
Haplotype frequencies of the ABCB1 C1236T and C3435T polymorphisms in drug-responsive and drug-resistant patients.
| ABCB1 C1236T-C3435T haplotype | Drug-resistant patients (N = 50) | Drug-responsive patients (N = 50) | ORs | 95% CI | p value | X 2 | ||
|---|---|---|---|---|---|---|---|---|
| n | % | n | % | |||||
| CC | 9 | 18 | 40 | 80 | 0.055 | 0.020-0.149 | ≤0.001 | 38.460 |
| CT | 15 | 30 | 4 | 8 | 4.929 | 1.503-16.158 | 0.009 | 7.860 |
| TC | 11 | 22 | 4 | 8 | 3.244 | 0.956-11.001 | 0.059 | 3.840 |
| TT | 15 | 30 | 2 | 4 | 10.286 | 2.209-47.902 | 0.003 | 11.980 |
Values (n and %). ORs: odds ratio; 95% CI: confidence interval; significant p value ≤ 0.05; X2: chi-square.