Table 9.
Haplotype frequencies of the ABCB1 C1236T, G2677T, and C3435T polymorphisms in drug-responsive and drug-resistant patients.
| ABCB1 C1236T-G2677T-C3435T haplotype | Drug-resistant patients (N = 50) | Drug-responsive patients (N = 50) | ORs | 95% CI | p value | X 2 | ||
|---|---|---|---|---|---|---|---|---|
| n | % | n | % | |||||
| CGC | 3 | 6 | 35 | 70 | 0.027 | 0.0073-0.1019 | ≤0.001 | 43.460 |
| TTC | 8 | 16 | 1 | 2 | 9.333 | 1.1210-77.7072 | 0.039 | 5.980 |
| TGC | 1 | 2 | 3 | 6 | 0.320 | 0.0321-3.1837 | 0.331 | 1.040 |
| CTT | 7 | 14 | 0 | 0 | 17.414 | 0.9665-313.7492 | 0.053 | 7.530 |
| CGT | 8 | 16 | 4 | 8 | 2.191 | 0.6145-7.8082 | 0.227 | 1.520 |
| TTT | 8 | 16 | 0 | 0 | 18.910 | 1.0607-337.1442 | 0.046 | 8.700 |
| CTC | 6 | 12 | 5 | 10 | 1.227 | 0.3490-4.3158 | 0.750 | 0.100 |
| TGT | 9 | 18 | 2 | 4 | 5.268 | 1.0766-25.7798 | 0.040 | 5.010 |
Values (n and %). ORs: odds ratio; 95% CI: confidence interval; significant p value ≤ 0.05; X2: chi-square.