Table 1. .
Baseline characteristics and LV global morphological and functional features derived from MRI in HCM patients and healthy volunteers
| Healthy volunteers (n = 19) |
Patients with HCM (n = 47) |
p-value (Mann–Whitney U-test) |
|
|---|---|---|---|
| Age (year） | 47 ± 14 (42, 56) |
50 ± 15 (46, 54) |
0.270 |
| Gender male (%） | 11 (57.9) | 35 (74.5) | 0.185 |
| BMI (kg/m2） | 23.2 ± 3.0 (21.8, 24.6) |
24.5 ± 4.3 (23.3, 25.8) |
0.217 |
| BSA (m2) | 1.7 ± 0.1 (1.7, 1.8) |
1.8 ± 0.2 (1.7, 1.9) |
0.120 |
| HR (beats/minute) | 69 ± 9 (65, 73) |
71 ± 13 (67, 75) |
0.498 |
| LVEDVI (ml/ m2) | 58.6 ± 17.2 (50.4, 66.9) |
62.2 ± 21.4 (55.9, 68.5) |
0.521 |
| LVESVI (ml/ m2) | 25.5 ± 10.7 (20.3, 30.6) |
25.6 ± 16.8 (20.7, 30.6) |
0.970 |
| LVSVI (ml/ m2) | 33.2 ± 7.2 (29.7, 36.6) |
36.6 ± 9.3 (33.9, 39.3) |
0.158 |
| LVEF (%) | 58.2 ± 6.3 (55.1, 61.2) |
60.4 ± 7.3 (58.3, 62.5) |
0.246 |
| LVmassI (g/m2) | 52.0 ± 7.8 (48.1, 55.9) |
80.0 ± 39.0 (68.2, 91.9) |
<0.001 |
Continuous variables are expressed as mean ± standard deviation(95% CI). HCM, hypertrophic cardiomyopathy; BMI, body mass index; BSA, body surface area; HR, heart rate; LVEDVI, left ventricular end-diastolic volume index; LVESVI, left ventricular end-systolic volume index; LVSVI, left ventricular stroke volume index; LVEF, left ventricular ejection fraction; LVmassI, left ventricular mass index.