Table 2. .
Native T1 and T2 values, PSWT, and EDTH in normal myocardial segments of healthy controls, non-hypertrophic, and hypertrophic myocardial segments of HCM patients
| Parameters | Healthy volunteers | HCM patients | ||
|---|---|---|---|---|
| Normal segments (n = 304) |
Non-hypertrophic segments (n = 588) |
Hypertrophic segments (n = 164) |
p-value (Kruskal–Wallis test) |
|
| EDTH (mm) | 6.3 ± 1.9 (6.1, 6.5) |
8.3 ± 2.8* (8.1,8.6） | 19.8 ± 5.8* (18.9, 20.7) |
<0.001 |
| Native T1 (ms) | 1237.1 ± 55.8 (1230.8, 1243.4) |
1283.6 ± 86.0* (1266.6, 1278.0） | 1336.6 ± 65.1* (1324.1, 1343.4) |
<0.001 |
| T2 (ms) | 40.4 ± 3.3 (40.0, 40.8) |
42.3 ± 3.9* (41.9, 42.5） |
43.8 ± 3.4* (43.2,44.2) |
<0.001 |
| PSWT (%) | 97.3 ± 51.8 (91.4, 103.1) |
100.7 ± 59.8 (94.7, 104.2） |
29.0 ± 20.0* (26.0, 32.2) |
<0.001 |
Continuous variables are expressed as mean ± standard deviation(95% CI). HCM, hypertrophic cardiomyopathy; EDTH, end-diastolic thickness; PSWT, percentage of systolic wall thickening. Column 3 and 4: * statistical significance compared to normal segments (column 2) using Mann–Whitney U-test.