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. Author manuscript; available in PMC: 2019 Dec 16.
Published in final edited form as: Neurobiol Learn Mem. 2019 Feb 20;165:107000. doi: 10.1016/j.nlm.2019.02.010

Fig. 1.

Fig. 1.

Male Shank3b−/−, Cntnap2−/−, Pcdh10+/−, and Fmr1 KO mice are hypoactive in the home-cage relative to sex-matched WT controls. (A,B) Shank3b−/− males exhibit significantly reduced horizontal activity compared to WT littermates. Expressed in 1-h bins (A) and by light/dark cycle (B). (C,D) Cntnap2−/− males have decreased horizontal activity compared to WT controls. Expressed in 1-h bins (C) and by light/dark cycle (D). (E,F) Pcdh10+/− males display significantly less horizontal activity than WT littermates. Expressed in 1-h bins (E) and by light/dark cycle (F). (G,H) Fmr1 KO males demonstrate significantly lower horizontal activity than WT controls. Expressed in 1-h bins (G) and by light/dark cycle (H). Mean ± standard error of the mean (s.e.m.) *p < 0.05, **p < 0.01, ***p < 0.001.