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. 2019 Dec 9;10:1460. doi: 10.3389/fphys.2019.01460

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Copyright © 2019 Pillai, Herzog, Seebeck, Pellegrini, Roth and Verrey.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of amino acid supplementation on body composition of CKD and Sham animals. CKD and Sham animals on different diets did not show changes in fat (black bars) and lean mass (gray bars for CKD animals and white for controls) with the exception of the AAA groups. They showed a reduction in fat mass that was significant in CKD (*p < 0.05) and with a p slightly above the 0.05 limit for the sham group, p = 0.06, ANOVA with Dunnett post hoc test. CKD: CD, n = 10; 8 + 10, n = 30; BCAA, n = 25; AAA, n = 25; EAA, n = 15; and NEAA, n = 10. Sham: n = 5 animals per group.