Schedule of study procedures.

Study procedure	Screening	Baseline	Day of surgery	Follow-up 1	Follow-up 2	End of study
		Day 1		4 weeks (±1w)	12 weeks (±2)
Review of HPB referrals	X
Eligibility Form	X
Surgeon’s Confirmation of Eligibility	X
Enrollment Log	X
Informed Consent Process	X
Baseline Case Report Form		X
Quality of Life (EORTC-QLQ-C30 and EORTC-QLQ-LMC21)		X		X	X
Surgery Worksheet (must be provided to surgeon prior to surgery)			X
Surgery Case Report Form			X
Pathology Case Report Form				X
Post-operative follow-up form (includes ECOG)				X	X
Minor Complication Form (only if applicable)				X	X
Major Complication Form (only if applicable)				X	X
Health Resource Utilization Form				X	X
Deidentify Data and send all study documents (enrollment log, case report forms and source)						X
Survival Information (if applicable)						X