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. 2019 Oct 11;8(10):e14001. doi: 10.2196/14001

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©Hideo Tsurushima, Masafumi Mizukami, Kenichi Yoshikawa, Tomoyuki Ueno, Yasushi Hada, Masahiko Gosho, Yutaka Kohno, Koichi Hashimoto, Yuichi Iizumi, Toshihiro Kikuchi, Akira Matsumura, Hit2016 Study Group. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 11.10.2019.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographic information, a link to the original publication on http://www.researchprotocols.org, as well as this copyright and license information must be included.

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Study design. This multicenter, randomized, parallel-group, controlled study has three phases (preintervention observation, intervention, and postintervention observation). Following primary registration, the patients undergo conventional rehabilitation and are monitored to detect stagnant recovery. Upon secondary registration prior to the intervention, the patients are randomized to undergo conventional rehabilitation aimed at regaining walking ability (control group), or a walking program involving the use of the Hybrid Assistive Limb (HAL) robotic exoskeleton (HAL group).