Table 1.
Clinical Characteristics of AML Patients
| Characteristics | Overall Cohort (n=134) | ||
|---|---|---|---|
| Favorable | Intermediate/Normal | Poor | |
| (n=17) | (n=91) | (n=26) | |
| Sex (male/female) | 9/8 | 45/46 | 10/16 |
| Age: median (range) | 52 (22–77) | 58 (21–88) | 63.5 (18–88) |
| Peripheral blast, % median (range) | 61 (35–90) | 72 (0–98) | 60 (30–99) |
| Bone marrow blast, % median (range) | 54 (0–86) | 37 (0–97) | 60 (30–99) |
| WBC count (109/L) median (range) | 22 (2–57) | 20 (1–203) | 11 (1–90) |
| Hemoglobin (g/dL) median (range) | 9 (7–11) | 10 (6–14) | 9 (7–13) |
| Platelet count (109/L) median (range) | 40 (9–149) | 52 (8–351) | 38 (9–148) |
| FAB classification | |||
| M0 | 0 | 7 | 7 |
| M1 | 4 | 25 | 6 |
| M2 | 6 | 20 | 7 |
| M4 | 6 | 23 | 4 |
| M5 | 0 | 14 | 0 |
| M6 | 0 | 1 | 1 |
| M7 | 1 | 1 | 1 |
| Cytogenetic abnormality | |||
| t(8;21) | 7 | 0 | 0 |
| inv(16) | 7 | 0 | 0 |
| Trisomy 8 | 0 | 0 | 6 |
| Complex | 0 | 0 | 16 |
Abbreviations: AML, acute myeloid leukemia; WBC, white blood cell; FAB, French-American-British.