Experimental paradigm and physical characteristics. Thirty-four to thirty-five day old animals were injected with MNU at time 0 (weeks) and followed for 20 weeks. Animals were progressively exercise trained (Ex), or remained sedentary, prior to and during exposure to hormone (H) pellets (A). Exercise training did not alter body weight (B), but did increase tumor latency (C) leading to smaller tumors (D) in exercise trained animals. *p < 0.05. Nulliparous (NP), early parity (EP), delayed parity (DP).