Table 3.

Frequencies of tested alleles and P-values of SNPs for 12 month and all time acute rejection for both European-American and African-American cohorts adjusted for clinical factors.

		European-American Recipients			African-American Recipients
SNP rs#	Gene	TAF	12 month P-value	All Time P-value	TAF	12 month P-value	All Time P-value
rs4148738	ABCB1	0.558	0.65	0.98	0.756	0.19	0.051
rs2269475	AIF	0.146	0.67	0.89	0.103	0.63	0.65
rs5186	AT1R	0.301	0.14	0.15	0.054	0.25	0.41
rs55637918	DEUP1 (CCDC67)	0.100	0.12	0.51	0.303	0.36	0.075
rs1024611	CCL2	0.272	0.35	0.23	0.188	0.97	0.51
rs2107538	CCL5	0.166	0.49	0.44	0.429	0.21	0.20
rs1799864	CCR2	0.098	0.18	0.31	0.173	0.74	0.94
rs1799987	CCR5	0.444	0.42	0.53	0.585	0.77	0.89
rs10490574	CD28	0.184	0.048	0.051	0.056	0.55	0.32
rs1129055	CD86	0.274	0.62	0.56	0.172	0.084	0.096
rs733618	CTLA4	0.081	0.17	0.26	0.141	0.53	0.14
rs5742909	CTLA4	0.095	0.0049	0.012	0.016	0.94	0.58
rs231775	CTLA4	0.391	0.034	0.018	0.399	0.27	0.13
rs3087243	CTLA4	0.427	0.96	0.85	0.200	0.53	0.63
rs4073	CXCL8	0.525	0.23	0.15	0.224	0.69	0.99
rs2515641	CYP2E1	0.892	0.66	0.80	0.395	0.82	0.68
rs776746	CYP3A5	0.068	0.21	0.050	0.694	0.67	0.56
rs4149257	EPHX2	0.254	0.54	0.41	0.787	0.44	0.19
rs1799963	F2	0.017	0.45	0.74	0.004	0.99	0.99
rs6025	F5	0.970	0.077	0.083	0.997	0.082	0.37
rs7851696	FCN2	0.114	0.23	0.37	0.220	0.19	0.55
rs1801274	FCGR2A	0.507	0.26	0.12	0.554	0.37	0.030
rs9296068	HLA-DOA	0.331	0.18	0.094	0.539	0.94	0.22
rs1063320	HLA-G	0.490	0.015	0.050	0.602	0.053	0.47
rs5498	ICAM1	0.422	0.90	0.84	0.189	0.92	0.44
rs1143634	IL1B	0.236	0.29	0.11	0.140	0.60	0.099
rs2069762	IL2	0.301	0.76	0.90	0.093	0.68	0.90
rs228942	IL2RB	0.176	0.25	0.42	0.095	0.22	0.19
rs2284033	IL2RB	0.425	0.65	0.94	0.430	0.76	0.44
rs657075	IL3	0.102	0.41	0.41	0.026	0.36	0.27
rs61527852	IL3	0.090	0.25	0.18	0.126	0.066	0.027
rs31480	IL3	0.221	0.71	0.82	0.145	0.77	0.36
rs2243250	IL4	0.143	0.98	0.78	0.657	0.92	0.84
rs1801275	IL4R	0.214	0.24	0.51	0.678	0.58	0.90
rs1524107	IL6	0.050	0.048	0.20	0.085	0.45	0.37
rs1800795	IL6	0.574	0.15	0.26	0.925	0.67	0.96
rs1800896	IL10	0.490	0.75	0.64	0.356	0.19	0.090
rs1800871	IL10	0.764	0.75	0.83	0.610	0.91	0.85
rs1800872	IL10	0.764	0.75	0.83	0.610	0.91	0.85
rs763780	IL17F	0.048	0.21	0.38	0.074	0.59	0.81
rs187238	IL18	0.270	0.11	0.094	0.215	0.67	0.83
rs2278293	IMPDH1	0.454	0.63	0.86	0.481	0.66	0.98
rs2278294	IMPDH1	0.350	0.88	0.67	0.425	0.84	0.52
rs11706052	IMPDH2	0.104	0.72	0.74	0.014	0.72	0.22
rs2430561	INFG	0.238	0.50	0.59	0.167	0.95	0.76
rs3807307	IRF5	0.476	0.68	0.95	0.293	0.041	0.052
rs5918	ITGB3	0.149	0.59	0.46	0.108	0.078	0.15
rs7096206	MBL2	0.779	0.20	0.51	0.844	0.66	0.58
rs5030737	MBL2	0.073	0.92	0.77	0.006	0.23	0.41
rs1800450	MBL2	0.134	0.67	0.75	0.034	0.75	0.50
rs1800451	MBL2	0.015	0.89	0.84	0.231	0.28	0.45
rs1801133	MTHFR	0.329	0.94	0.76	0.107	0.84	0.45
rs2426295	NFATC2	0.073	0.22	0.82	0.063	0.36	0.38
rs28362491	NFKB1	0.383	0.29	0.71	0.513	0.22	0.34
rs8904	NFKBIA	0.380	0.87	0.42	0.594	0.93	0.75
rs2227982	PDCD1	0.009	0.24	0.52	0.01	0.99	0.69
rs12734919	PTGS2	0.178	1.00	0.68	0.035	0.49	0.31
rs2476601	PTPN22	0.880	0.95	0.84	0.985	0.52	0.77
rs7137890	PTPRO	0.343	0.18	0.34	0.174	0.79	0.92
rs7574865	STAT4	0.773	0.90	0.84	0.845	0.94	0.68
rs1800470	TGFB	0.620	0.37	0.93	0.546	0.87	0.69
rs1800471	TGFB	0.077	0.47	0.42	0.067	0.89	0.96
rs3775291	TLR3	0.292	0.70	0.76	0.074	0.35	0.27
rs4986790	TLR4	0.052	0.30	0.19	0.070	0.95	0.78
rs10759932	TLR4	0.139	0.30	0.78	0.238	0.0089	0.0046
rs1800629	TNF	0.195	0.75	0.90	0.110	0.86	0.55
rs1625895	TP53	0.882	0.97	0.98	0.726	0.72	0.49
rs17868320	UGT1A9	0.060	0.46	0.50	0.025	0.79	0.54
rs6714486	UGT1A9	0.061	0.41	0.44	0.197	0.96	0.36
rs7439366	UGT2B7	0.462	0.48	0.19	0.706	0.068	0.17
rs699947	VEGFA	0.507	0.23	0.25	0.791	0.29	0.32
rs3025007	VEGFA	0.456	0.83	0.82	0.334	0.61	0.62
rs2961920	MIR146A	0.768	0.59	0.45	0.576	0.0019	0.00011
rs4759316	MIR196A2	0.558	0.84	0.68	0.604	0.96	0.95
rs3746436	MIR499A	0.189	0.48	0.69	0.165	0.43	0.38

TAF – Tested allele frequency