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. 2019 Jun 3;29(6):760–777. doi: 10.1089/thy.2018.0416

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Copyright 2019, 2019 American Thyroid Association, Mary Ann Liebert, Inc., publishers, and American Heart Association, Inc.

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FIG. 3. — Effect of thyroid hormones on the cardiomyocyte via genomic and nongenomic actions from Reference (2). Reproduced with permission from Jabbar et al. (2). Copyright © 2017, Springer Nature Publishing AG. DIO2, type 2 iodothyronine deiodinase; DIO3, type 3 iodothyronine deiodinase; MAPK, mitogen-activated protein kinase; MYH6, myosin heavy chainα; MYH7, myosin heavy chainβ; PI3K, phosphoinositide 3 kinase; PLN, phospholamban; rT3, reverse T3; SERCA, sarco/endoplasmic reticulum Ca²⁺-ATPase; T2, diiodothyronine; T3, triiodothyronine; T4, thyroxine; TR, thyroid receptor; TRE, thyroid hormone response element.