Table 2.
Outcome | Blended CBTa | Standard CBT | Full sample | Blended CBT vs standard CBT | ||||
|
n | Value | n | Value | n | Value | b (95% CI) | |
Depression severity (IDS-SRb), mean (SD) |
|
|
|
|
|
|||
|
Baseline | 53 | 45.2 (12.1) | 49 | 41.5 (11.6) | 102 | 43.4 (12.0) | Ref |
|
10 weeks | 41 | 31.9 (12.7) | 35 | 32.0 (17.5) | 76 | 32.0 (15.0) | −3.36 (−8.20, 1.16) |
|
20 weeks | 35 | 30.7 (16.1) | 30 | 27.1 (15.7) | 65 | 29.0 (15.9) | 1.50 (−6.22, 9.02) |
|
30 weeks | 36 | 29.5 (17.2) | 29 | 21.1 (15.4) | 65 | 25.8 (16.9) | 8.92 (−1.05, 18.50) |
QALYsc (EQ-5D-3L), mean (SD) |
|
|
|
|
|
|||
|
Baseline | 53 | 0 | 49 | 0 | 102 | 0 | Ref |
|
10 weeks | 41 | 0.09 (0.05) | 35 | 0.10 (0.05) | 76 | 0.10 (0.05) | −0.01 (−0.04, 0.01) |
|
20 weeks | 35 | 0.20 (0.10) | 30 | 0.24 (0.09) | 65 | 0.22 (0.10) | −0.02 (−0.06, 0.03) |
|
30 weeks | 36 | 0.31 (0.16) | 29 | 0.39 (0.13) | 65 | 0.35 (0.15) | −0.03 (−0.10, 0.04) |
Reliable change (IDS-SR), n (%) | ||||||||
|
Baseline | 53 | 0 | 49 | 0 | 102 | 0 | Ref |
|
10 weeks | 41 | 27 (66) | 35 | 19 (54) | 76 | 46 (61) | 0.89 (−1.17, 2.72) |
|
20 weeks | 35 | 21 (60) | 30 | 19 (63) | 65 | 40 (62) | 0.07 (−1.69, 2.01) |
|
30 weeks | 36 | 22 (61) | 29 | 23 (79) | 65 | 45 (69) | −0.48 (−2.49, 1.47) |
Current depressive episode (MINI-Plus)d, n (%) |
|
|
|
|
|
|||
|
Baseline | 53 | 52 (98) | 49 | 48 (98) | 102 | 100 (98) | Ref |
|
10 weeks | 44 | 27 (61) | 41 | 18 (44) | 85 | 45 (44) | 1.44 (−2.19, 5.07) |
|
20 weeks | 44 | 24 (55) | 40 | 15 (38) | 84 | 39 (38) | 1.30 (−2.35, 5.00) |
|
30 weeks | 39 | 15 (39) | 37 | 13 (35) | 76 | 28 (28) | 0.32 (−3.35, 4.00) |
aCBT: cognitive behavioral therapy.
bIDS-SR: Inventory of Depressive Symptomatology, self-report version.
cMINI-Plus: Mini-International Neuropsychiatric Interview Plus.
dQALYs: quality-adjusted life-years.