Table 1. PHE1 ChIP-seq read mapping and peak calling information.

Peak calling was done using the ChIP sample and its respective Input sample as control. The fraction of peaks present in both replicates was determined as the percentage of peaks for which spatial overlap between Replicate 1 and Replicate 2 peaks is observed (see Materials and methods).

Sample	No. of sequenced reads	% of mapped reads	No. of called ChIP-seq peaks	% of ChIP-seq peaks present in both replicates
Replicate 1 PHE1::PHE1–GFP ChIP	17,037,975	65.3	2818	88.5
Replicate 1 PHE1::PHE1–GFP Input	24,276,095	71.1
Replicate 2 PHE1::PHE1–GFP ChIP	21,838,147	70.5	4521	55.2
Replicate 2 PHE1::PHE1–GFP Input	23,372,778	70.7