Table 3. Significant statistical analysis clusters for AD, aMCI-m, aMCI-s and NC (Monte Carlo simulation corrected for multiple comparisons).

hemisphere		cluster	cluster size(mm2)	Talairach			CWP	cortical region
				x	y	z
AD vs aMCI-m	left	1	1,152.2	-40.5	-52.8	-14.1	< 0.01	fusiform
AD vs aMCI-s	left	1	6,997.7	-35.3	-50.8	-12.4	< 0.01	fusiform
		2	2,350.9	-7.0	-49.8	18.5	< 0.01	isthmus cingulate
		3	2,321.4	-42.2	-15.7	-9.3	< 0.01	superior temporal
		4	1,146.2	-33.5	12.4	23.0	0.01	caudal middle frontal
	right	1	2,398.8	19.3	-83.7	-2.2	< 0.01	lateral occipital
AD vs NC	left	1	17,196.7	-31.0	-52.2	-3.7	< 0.01	fusiform
		2	6,979.2	-24.7	30.5	29.1	< 0.01	rostral middle frontal
		3	2,626.7	-13.5	-40.9	31.5	< 0.01	isthmus cingulate
		4	2,239.5	-21.5	27.7	-11.7	< 0.01	lateral orbitofrontal
	right	1	9,284.5	35.2	4.7	-13.4	< 0.01	insula
		2	6,581.7	33.7	14.9	22.3	< 0.01	caudal middle frontal
		3	2,852.0	20.3	32.7	31.2	< 0.01	superior frontal
		4	2,363.5	43.1	-48.7	18.7	< 0.01	inferior parietal
aMCI-m vs aMCI-s	left	1	1,176.7	-61.9	-35.5	-9.4	< 0.01	middle temporal
aMCI-m vs NC	left	1	2,482.3	-43.4	-47.4	12.8	< 0.01	bankssts
		2	1,761.0	-36.9	-0.8	-12.8	< 0.01	insula
		3	1,319.3	-32.0	-38.1	-7.6	< 0.01	parahippocampal
		4	928.8	-39.1	27.8	15.1	0.04	rostral middle frontal
	right	1	1,357.4	50.0	4.4	18.9	< 0.01	precentral
		2	1,312.5	10.6	-54.1	18.7	< 0.01	precuneus
		3	913.2	28.3	-60.5	-8.2	0.03	fusiform
aMCI-s vs NC	left	1	1,646.2	-19.3	29.1	33.5	< 0.01	superior frontal
	right	1	1,400.1	24.1	-52.2	48.2	< 0.01	superior parietal

The size of the significant cluster, Talairach coordinates and cortical areas corresponding to the most significant vertex within the cluster, cluster-wise p value (CWP) are shown.