Table 5. Summary of multidimensional external validation results base on multiple databases.

Database	MUC1/MUC1		ITGAX/CD11c		Results
	Cancer	Normal	Cancer	Normal
Oncomine	↑	↓	-	-	Across ten analysis, MUC1 was highly expressed in primary STS compared to normal tissue while CD11c (Gene symbol: ITGAX) showed no difference (Supplementary Figure 5).
CCLE	↑	NA	-	NA	At the cellular level, MUC1 was expressed in various STS cell lines while ITGAX expression was low STS cell lines (Supplementary Figure 6).
cBioPortal	↑	↓	-	-	MUC1 and ITGAX were highly expressed in primary STS compared to some other types of cancer and they had a significant co-expression pattern in STS (Supplementary Figure 7).
GTEx	NA	↓	NA	↓	MUC1 and ITGAX were lowly expressed in normal adipose tissue and smooth muscle tissue (Supplementary Figure 8).
UCSC Treehouse	↑	↓	-	-	MUC1 was highly expressed in primary STS compared to normal soft tissue while ITGAX did not (Supplementary Figure 8).
The Human Protein Atlas	NA	ND	NA	ND	Protein MUC1 and CD11c were almost not detected in normal adipose tissue and smooth muscle tissue (Supplementary Figure 9).

Note: “↑” was defined as a significantly upregulated gene; “↓” was defined as a significantly downregulated gene; “-” was defined as a a gene with no significant difference in expression; “NA” was defined as “Not available”; “ND” was defined as “Not detected”;

Abbreviations: CCLE: Cancer Cell Line Encyclopedia; GTEx: Genotype-Tissue Expression; UCSC: University of California, Santa Cruz